Keywords
How to Cite
Abstract
The article describes the effect of selenium on the functional state of patients with various autoimmune diseases of the endocrine system. It has been established that selenium has an antioxidant protection of the body of patients in therapeutic and prophylactic doses. Maintaining the physiological concentration of selenium is a necessary condition for maintaining health and preventing diseases of the thyroid gland, and when adding the organic form, it is more effective in patients with autoimmune thyroiditis, which is confirmed by a number of immunological studies.
References
Winther KH, Rayman MP, Bonnema SJ, Hegedüs L. Selenium in thyroid disorders – essential knowledge for clinicians. Nature Reviews. Endocrinology.2020;16:165-176.
Тронько М, Болгов М, Большова О. Мала енциклопедія ендокринолога. Основні нозології та синдроми. 2022:424.
Комісаренко ЮІ, Михальчишин РП. Ендокринологія. 5-те вид. 2020:536.
Гонський ЯІ, Максимчук ТП. Біохімія людини [Human biochemistry]. Тернопіль: ТДМУ, 2019:732.
McLachlan SM, Aliesky H, Banuelos B, Hee SSQ, Rapoport B. Variable effects of dietary selenium in mice that spontaneously develop a spectrum of thyroid autoantibodies. Endocrinology. 2017;158:3754-3764.
Zuo Y, Li Y, Gu X, Lei Z. The correlation between selenium levels and autoimmune thyroid disease: a systematic review and meta-analysis. Annals of Palliative Medicine. 2021;10:4398-4408.
Samuels MH. Higher selenium intake reduces the prevalence of hyperthyroidism in men, but does not affect Graves’ disease clinical severity in a mouse model. Clinical Thyroidology. 2019;31:182-184.
Winther KH, Papini E, Attanasio R, Negro R, Hegedüs L. A 2018 European Thyroid Association survey on the use of selenium supplementation in Hashimoto’s thyroiditis. European Thyroid Journal. 2020;9:99-105.
Mahmoudi L, Mobasseri M, Ostadrahimi A, Pourmoradian S, Soleimanzadeh H, Kafili B. Effect of selenium-enriched yeast supplementation on serum thyroidstimulating hormone and anti-thyroid peroxidase antibody levels in subclinical hypothyroidism: randomized controlled trial. Advanced Biomedical Research. 2021;10:33.
Davidson’s Principles and Practice of Medicine, 23rd Edition, 2018.
Власенко МВ, Біляєва КС, Паламарчук АВ. та ін. Лабораторна діагностика, діагностичні тести в ендокринології. К.: Видавничий дім Медкнига, 2021:120.
Власенко МВ, Вернигородський ВС, Паламарчук АВ та ін. Інтенсивна терапія в ендокринології (невідкладні стани). К: Видавничий дім Медкнига, 2021:144.
Qiu Z, Geng T, Wan Z, Lu Q, Guo J, Liu L, Pan A, Liu G. Serum selenium concentrations and risk of all-cause and heart disease mortality among individuals with type 2 diabetes. American Journal of Clinical Nutrition. 2022;115:53-60.
Ruggeri RM, Trimarchi F. Iodine nutrition optimization: are there risks for thyroid autoimmunity? J Endocrinol Invest. 2021;44(9):1827-35. doi: 10.1007/s40618-021-01548-x.
Ruggeri RM, D’Ascola A, Vicchio TM, Campo S, Gianì F, Giovinazzo S, Frasca F, Cannavò S, Campennì A, Trimarchi F. Selenium exerts protective effects against oxidative stress and cell damage in human thyrocytes and fibroblasts. Endocrine. 2020;68:151-162.