Comparative structural characteristics of the chewing muscle in iododefficient condition and iododefficiency with the use of strumogenes

Abstract

The aim of this study was to compare the features of the morphological organization of the vascular bed and muscle fibers of the masticatory muscle of rats in experimentallymodeled iodine deficiency and iodine deficiency with the addition of strumogenic substances. The results of biochemical studies showed a decrease in the content of thyroid hormones, especially in experimental group III. In the vascular bed of the masticatory muscle, the thickness of the arterial wall increases due to edematous changes, which are confirmed at the submicroscopic level. The number of hemocapillaries in 1 μm2 decreased by 6.55% (p<0.01). Muscle fibers are characterized by uneven alternation of dark and light stripes with edematous changes, which is confirmed by an increase in the diameter of the cross section in all types of muscle fibers and the results of ultrastructural examination. In the study of LDH activity, there was a 1.5-fold decrease in the number of muscle fibers with intermediate succinate dehydrogenase activity with a simultaneous increase in muscle fibers with low succinate dehydrogenase activity (2-fold), which can be explained by a change in blood supply.